Related Experiment Video
Updated: Jul 21, 2026

Intravital Microscopy of the Mouse Brain Microcirculation using a Closed Cranial Window
Published on: November 18, 2010
[The hematocrit in the microcirculatory bed of the brain]
Abstract:
Concentration of erythrocytes (hematocrit) was assessed in blood samples taken from small veins of the brain and the hindlimbs of rabbits. Its values were regularly found to be higher by 20% in cerebral vessels than in the hindlimbs. These results corroborate our previous conclusion about preferential distribution of erythrocytes along the arterial ramifications to the brain where the metabolic rate and the blood flow are higher than in other parts of the body. The hematocrit in capillaries of the cerebral cortex was found to be higher than in the veins draining blood from its networks. During ischemia in the cerebral hemispheres the erythrocyte concentration regularly decreased both in the cortex capillaries and in the veins. These changes were independent of the systemic hematocrit, which remained unchanged under these conditions.
Related Concept Videos
The Blood-brain Barrier
Composition of Blood
Formed elements constitute the remaining 45% of the blood volume. These...
Capillary Beds
Capillaries connect arterioles, small branches of arteries, to venules,...
Hemorrhagic Stroke ll: Pathophysiology
Cerebral Edema ll: Pathophysiology

