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Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues

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Published on: February 17, 2017

Trehalose Toxicity in Cuscuta reflexa: CORRELATION WITH LOW TREHALASE ACTIVITY.

K Veluthambi¹, S Mahadevan, R Maheshwari

¹Department of Biochemistry, Indian Institute of Science, Bangalore 560 012, India.

Plant Physiology

|December 1, 1981

Summary

This summary is machine-generated.

Alpha,alpha-trehalose is toxic to plants like Cuscuta reflexa due to low trehalase activity, causing growth inhibition. This disaccharide may be toxic to higher plants if it accumulates.

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Area of Science:

Plant physiology
Biochemistry
Toxicology

Background:

Alpha,alpha-trehalose is a disaccharide found in various organisms.
Its role and effects in higher plants, particularly parasitic ones like Cuscuta reflexa, are not fully understood.
Trehalase is an enzyme that hydrolyzes trehalose.

Purpose of the Study:

To investigate the toxic effects of alpha,alpha-trehalose and its analogs on Cuscuta reflexa.
To determine the role of trehalase activity in plant response to trehalose.
To assess the potential toxicity of trehalose to higher plants in general.

Main Methods:

In vitro growth experiments with various angiospermic plants.
Determination of trehalase activity in plant tissues.
Treatment with trehalose, 2-aminotrehalose, 4-aminotrehalose, and trehalosamine.

Main Results:

Alpha,alpha-trehalose and its analogs caused blackening and inhibited growth in Cuscuta reflexa.
Cuscuta reflexa exhibited very low trehalase activity, leading to trehalose accumulation.
Trehalose inhibited growth in Lemna (duckweed), with irreversible loss of growth potential upon addition of trehalosamine.

Conclusions:

The toxicity of trehalose in Cuscuta reflexa is attributed to its low trehalase activity and subsequent accumulation.
Accumulated trehalose interferes with growth processes in plants.
Trehalose may be generally toxic or inhibitory to higher plants, and plant trehalase activity is crucial for mitigating these effects from environmental sources.