Protein C and renal pathology in Ivory Coast population

Protein C activity was determined in 80 patients clinically divided into 3 groups: I) nephrotic syndrome, II) chronic renal insufficiency and III) terminal uremia, requiring maintenance dialysis. Results were compared to physiological values in 100 healthy Ivorian adults. In nephrotic syndrome, protein C activity was significantly higher, while in renal insufficiency and terminal uremia, it was significantly lower than in normal subjects.