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[The correlations between changes in coronary vascular tonus and eicosanoid formation during an immune action on the
Fiziologicheskii Zhurnal SSSR Imeni I. M. Sechenova
|September 1, 1991
Abstract:
Activation of the lipoxygenase way of the arachidone acid metabolism was shown to play a major role in development of pathological processes in the heart. The data on interrelationship between the formation of eucosanoids and the character of the heart immune response to inhibition of lipoxygenase, were obtained. A correlation was found between the increase in the LTS4 in the blood and the development of prolonged constrictor responses of the coronary vessels.