Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Geographical variation in selection, from phenotypes to molecules.

John K Kelly1

  • 1Department of Ecology and Evolutionary Biology, University of Kansas, Lawrence, Kansas 66045, USA. jkk@ku.edu

The American Naturalist
|May 4, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adaptive transgenerational plasticity through priming in response to neighbor density in Mimulus platycalyx.

PloS one·2026
Same author

Comparative Analyses of Four Reference Genomes Reveal Exceptional Diversity and Weak Linked Selection in the Yellow Monkeyflower (Mimulus guttatus) Complex.

Molecular ecology resources·2025
Same author

Measuring natural selection on the transcriptome.

The New phytologist·2025
Same author

Are you with me? Co-occurrence tests from community ecology can identify positive and negative epistasis between inversions in Mimulus guttatus.

PloS one·2025
Same author

Editorial: The impacts of the mating system and inbreeding depression in natural plant populations and crop systems.

Frontiers in plant science·2025
Same author

Testing the evolutionary theory of inversion polymorphisms in the yellow monkeyflower (Mimulus guttatus).

Nature communications·2024
Same journal

Traffic Reduction during COVID-19 Lockdowns Benefited Species Already Tolerant of Noise Pollution: An Acoustic Analysis.

The American naturalist·2026
Same journal

On Pachycephalosaurs, Trade-Offs, and the Historical Genesis of Sociosexual Display Structures.

The American naturalist·2026
Same journal

Structured Landscapes Promote Persistence by Favoring Prudent Predators.

The American naturalist·2026
Same journal

Can Carbon Economy Explain Leaf Dynamic Seasonality in a Tropical Seasonal Rainforest?

The American naturalist·2026
Same journal

Behavior and Physiology Outpace Form When Linking Traits to Ecological Responses within Populations: A Meta-Analysis.

The American naturalist·2026
Same journal

Seminal Fluid Proteins as Regulation Factors for Optimizing Reproduction: A Modeling Approach.

The American naturalist·2026
See all related articles

Selection can alter quantitative genetic variation without changing linked molecular variation. This challenges assumptions in gene sequence surveys, especially in species with low migration.

Area of Science:

  • Evolutionary Genetics
  • Population Genetics
  • Genomics

Background:

  • Molecular technologies enable the study of quantitative trait loci (QTLs) and gene sequence variation.
  • Understanding gene sequence evolution in regions with QTLs under varying selection is crucial.
  • Geographical variation in selection can cause phenotypic differentiation.

Purpose of the Study:

  • To investigate gene sequence evolution within genomic regions containing QTLs using a simulation model.
  • To examine how selection on a trait with geographical variation impacts molecular variation patterns.

Main Methods:

  • Development of a simulation model for gene sequence evolution.
  • Modeling QTLs influencing a trait under geographically varying selection pressures.

Related Experiment Videos

  • Analysis of molecular variation patterns at sites linked to QTLs.

    • Main Results:

    • Selection can significantly alter quantitative genetic variation without changing molecular variation at closely linked sites.
    • The likelihood of rejecting neutrality is often low, even with large gene sequence samples.
    • Strong selection combined with low migration (common in plants) can be an exception, affecting molecular variation.

    Conclusions:

    • Gene sequence variation may not always reflect the strength of selection on linked quantitative traits.
    • Findings have implications for interpreting gene sequence surveys and the relationship between molecular and quantitative variation.
    • The weak connection between molecular and quantitative trait variation may be common.