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Updated: Aug 8, 2026

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
Published on: April 9, 2012
Discontinuation of respiratory isolation for possible tuberculosis: do two negative sputum smear results suffice?
Charles S Bryan1, Deborah J Rapp, Cynthia A Brown
1University of South Carolina School of Medicine, Palmetto Richland Memorial Hospital, Two Medical Park, Columbia, SC 29203, USA. cbryan@gw.mp.sc.edu
Abstract:
Analysis of acid-fast bacillus smear results at a hospital with a moderate incidence of tuberculosis confirms recent recommendations that 2 negative smear results suffice for discontinuation of respiratory isolation. Use of polymerase chain reaction analysis further increases the confidence with which the diagnosis of active tuberculosis likely to be transmitted to others can be excluded.
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