Chromatin and epigenetics in development: blending cellular memory with cell fate plasticity
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Updated: Aug 8, 2026

Cultivate Primary Nasal Epithelial Cells from Children and Reprogram into Induced Pluripotent Stem Cells
Published on: March 10, 2016
1Institute of Human Genetics, CNRS, Montpellier, France. giacomo.cavalli@igh.cnrs.fr
Abstract:
The epigenetic regulation of chromatin structure and composition has often been studied molecularly in the context of specific DNA-dependent processes. However, epigenetics also play important global roles in shaping and maintaining cell identity, and in patterning the body plan during normal development. Moreover, alterations in epigenetic regulation are involved in many diseases, including cancer. The advances in our understanding of the impact of epigenetics in development and disease were discussed at a recent Keystone symposium.
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