Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Reusable gels for germanium-68 sources.

R S Tilbury1, W F Broussard, M J Youngerman

  • 1Department of Nuclear Medicine, University of Texas M.D. Anderson Cancer Center, Houston 77030.

International Journal of Radiation Applications and Instrumentation. Part A, Applied Radiation and Isotopes
|January 1, 1991
PubMed
Summary

New radioactive sources using germanium-68 (68Ge) in water-soluble gels offer a stable, long-lived alternative. These gels simplify preparation and reduce radiation exposure for positron emission tomography (PET) operators.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nuclear shell structure governs short-range nucleon pairing.

Nature·2026
Same author

Search for Light Pseudoscalar Bosons, Pair-Produced in Higgs Boson Decays in the Four-Electron Final State in Proton-Proton Collisions at sqrt[s]=13  TeV.

Physical review letters·2026
Same author

First Evidence for Mixing-Induced CP Violation in B_{s}^{0}→J/ψϕ(1020) Decays in pp Collisions at sqrt[s]=13  TeV.

Physical review letters·2026
Same author

Observation of Suppressed Charged-Particle Production in Ultrarelativistic Oxygen-Oxygen Collisions.

Physical review letters·2026
Same author

Measurement of D^{0} Meson Photoproduction in Ultraperipheral Heavy Ion Collisions.

Physical review letters·2026
Same author

Observation of tWZ Production at the CMS Experiment.

Physical review letters·2026

Area of Science:

  • Radiochemistry
  • Materials Science
  • Nuclear Medicine

Background:

  • Short-lived germanium-68 (68Ge) is commonly used in positron emission tomography (PET).
  • Preparation of 68Ge/68Gallium (68Ga) generators is frequent and involves radiation exposure.
  • Existing radioactive sources may lead to waste of radioactive material.

Purpose of the Study:

  • To evaluate water-soluble gels (gelatin and Carbowax) as matrices for long-lived radioactive sources.
  • To assess the potential of these gel sources as replacements for short-lived 68Ga in PET attenuation correction.
  • To reduce the frequency of radioactive source preparation and associated radiation exposure.

Main Methods:

  • Mixing radioactive 68Ge solutions with gelatin and Carbowax to form water-soluble gels.

Related Experiment Videos

  • Evaluating the physical properties of the gels, including melting and solidification points.
  • Assessing the suitability of the gels as long-lived radioactive sources for PET applications.

    • Main Results:

    • The developed gels effectively incorporate radioactive 68Ge, forming stable sources.
    • These gels exhibit properties suitable for use as radioactive sources with a long half-life (280 days).
    • The concentration of 68Ge can be adjusted, minimizing waste.

    Conclusions:

    • Gelatin and Carbowax gels are viable matrices for creating long-lived 68Ge radioactive sources.
    • These novel gel sources have the potential to replace short-lived 68Ga in PET attenuation correction.
    • The use of these gels can decrease preparation frequency and reduce radiation exposure for PET operators.