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Plasma cyclic AMP increases in hamsters following exposure to a graded footshock stressor
K L Huhman1, M A Hebert, J L Meyerhoff
1Department of Medical Neurosciences, Walter Reed Army Institute of Research, Washington, D.C.
Psychoneuroendocrinology
|January 1, 1991
Abstract:
To assess the utility of plasma cyclic AMP (cAMP) as a sensitive physiological index of an animal's arousal level, we exposed male hamsters to various intensities (0.0-2.0 mA) of a footshock stressor. The plasma cAMP response was directly related to stimulus intensity. Ratings of behavioral arousal were positively correlated with plasma cAMP values. We conclude that plasma cAMP may be a useful index of arousal.