[Monitoring and controlling of renal transplant infection]

Infection is still the leading cause of death in renal transplantation. How to control it is an urgent problem to be solved. Bacteria culture, computerized monitoring methods, OKT monoclonal antibody techniques and radioimmunoassay (RIA) were applied to study the cause, monitoring and prevention of the infection. The result showed: Helper/suppressor lymphocyte ratio equalling 1.08 could be taken as a threshold value for infection diagnosis. 22 patients were colonized by Gram-negative bacilli on the body surface. Among them, 15 were infected with the same bacteria in the wound, urine, blood and lung. 6 out of 7 cases with serious infections had been colonized by Gram-negative bacilli on the surface of the whole body. Computer analysis indicated that the methods of using antibiotic should be improved. In summary, preserving adequate anti-infection immunity and effective control of rejection is the key point of this study.