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A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
[A study on aetiological factors of primary hepato-carcinoma in Tianjin China]
1Department of Epidemiology, Tianjin Medical College.
Abstract:
In order to investigate the possible risk factors of primary hepato-carcinoma (PHC) in Tianjin, 122 clinical diagnosed PHC patients and matched hospital controls were interviewed and 99 pairs of their blood samples were examined for HBV. The findings confirmed the strong association between HBV infection and PHC. The individual's immune state during HBV infection might be an important factor for PHC development. Histories of hepatitis and cirrhosis and family history of PHC were risk factors of PHC. Cigarette smoking might have association with PHC. Smoking for more the years of, the higher the risk of PHC. The present study did not find association between PHC and drinking water, dietary habits, alcohol consumption, histories of blood transfusion and injection, exposure to pesticides and poison.
