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Recurrent injection site reactions from interferon beta 1-b

Lena Samuel1, Eve J Lowenstein

  • 1SUNY Health Science Center Department of Dermatology, Brooklyn, NY 11203, USA.

Journal of Drugs in Dermatology : JDD
|May 6, 2006
PubMed

Recombinant human interferon beta-1b is an immune-modulatory drug used for a variety of conditions including multiple sclerosis (MS). Skin reactions to therapeutic use of injectable interferon beta-lb are relatively common, including injection site reactions and exacerbation of underlying skin disease. Injection site reactions are seen much more frequently in females. We discuss a case of prolonged susceptibility to injection site reaction with over a decade of use of interferon beta 1-b for MS. Given the prevalence of such reactions, the dermatologist should be aware of the phenomenon and that it frequently does not necessitate discontinuation of therapy.

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