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Severe Ecstasy poisoning in a toddler
1Department of Critical Care Medicine, Lawes Bridge, Torquay, Devon, TQ2 7AA, UK. mike_r_duffy@hotmail.com
Insights
A toddler experienced a critical overdose from Ecstasy (MDMA), developing seizures and hyperthermia. Prompt medical intervention led to a full recovery with no lasting effects.
Area of Science:
- Pediatric Toxicology
- Emergency Medicine
- Pharmacology
Background:
- Accidental overdose of recreational drugs in toddlers is a rare but serious medical emergency.
- Ecstasy (3,4-methylenedioxymethamphetamine) is a synthetic psychoactive drug with potential for severe toxicity.
Observation:
- A 17-month-old toddler presented with critical illness following accidental ingestion of a single Ecstasy tablet.
- Clinical manifestations included generalized tonic-clonic seizures, hyperthermia (38.5°C), tachycardia (150 bpm), and hypertension.
- Rapid retrieval of the intact tablet from the oral cavity did not prevent rapid systemic absorption and toxicity.
Findings:
- Seizures required intubation and mechanical ventilation for management.
- Therapeutic hypothermia was employed to reduce hyperthermia.
- The child demonstrated a rapid recovery following intensive care management.
Implications:
- This case highlights the critical risk of pediatric recreational drug overdose.
- Early recognition and aggressive supportive care are crucial for favorable outcomes in pediatric MDMA toxicity.
- Accidental ingestion of illicit substances poses a significant public health concern requiring parental education and vigilance.
Abstract:
A 17-month-old toddler became critically ill after an accidental overdose with 'Ecstasy'. A single tablet was quickly retrieved intact from under her tongue, but within 5 min the child developed generalised tonic-clonic seizures requiring immediate transfer to hospital. She also had hyperthermia (38.5 degrees C), tachycardia (150 beats.min(-1)) and hypertension. Treatment to terminate the seizures necessitated intubation and ventilation, and cooling measures brought the temperature within normal limits. The child was admitted to the intensive care unit and made a rapid recovery. She was discharged to the ward 12 h later, and had no long-term sequelae.
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