Related Experiment Videos
Post kala-azar dermal leishmaniasis: the Kenyan experience
R Muigai1, G S Gachihi, C N Oster
1Clinical Research Centre, Kenya Medical Research Institute, Nairobi.
East African Medical Journal
|October 1, 1991
Summary
Post kala-azar dermal leishmaniasis (PKDL) is a skin condition that can follow visceral leishmaniasis treatment. Lesions varied but resolved with self-cure or sodium stibogluconate therapy.
Area of Science:
- Dermatology
- Infectious Diseases
- Parasitology
Background:
- Post kala-azar dermal leishmaniasis (PKDL) is a recognized sequela following treatment for visceral leishmaniasis.
- PKDL presents a diagnostic and therapeutic challenge in endemic regions.
Purpose of the Study:
- To describe the clinical presentation and outcomes of patients diagnosed with PKDL.
- To evaluate the efficacy of sodium stibogluconate in managing PKDL.
Main Methods:
- Retrospective review of twelve patients diagnosed with PKDL between 1981 and 1985.
- Clinical data collection including lesion type and treatment response.
Main Results:
- Patient presentations ranged from macular hypopigmented lesions to generalized nodular forms.
- Complete lesion clearance was observed in all patients.
- Clearance was achieved through spontaneous self-cure or treatment with sodium stibogluconate.
Conclusions:
- PKDL exhibits diverse clinical manifestations.
- Effective management of PKDL can be achieved with sodium stibogluconate or may resolve spontaneously.