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Published on: June 2, 2014
Epilepsy and migraine headache: is there a connection?
1Arkansas Children's Hospital, 800 Marshall St, Slot #512-15, Little Rock, AR 72202, USA. stevensonsharon@uams.edu
Insights
Pediatric epilepsy patients show a higher prevalence of migraine headaches compared to the general population. A family history of epilepsy is more common than a family history of migraine in these children.
Area of Science:
- Neurology
- Pediatrics
- Genetics
Background:
- Epilepsy and migraine are common neurological disorders in children.
- Investigating comorbidities like migraine in pediatric epilepsy is crucial for comprehensive care.
Purpose of the Study:
- To determine the prevalence of migraine headaches in pediatric patients diagnosed with epilepsy.
- To examine the incidence of family history of both epilepsy and migraine in this cohort.
Main Methods:
- Retrospective chart review of 475 pediatric epilepsy patients.
- Data collection included demographics, headache, migraine, and family history of neurological disorders.
- Patients were identified via ICD-9-CM codes from a major teaching hospital's pediatric neurology clinic.
Main Results:
- Migraine prevalence in pediatric epilepsy patients was 14.7%, significantly higher than the general population (2.7%-11%).
- A positive family history of epilepsy was found in 20.6% of patients.
- Only 4.7% of patients reported a family history of migraine.
Conclusions:
- The findings highlight a significant comorbidity between epilepsy and migraine in children.
- A positive family history of epilepsy supports genetic links in some epilepsy cases.
- Clinicians should consider screening for coexisting disorders when diagnosing primary conditions in pediatric neurology.
Introduction:
This study investigated the prevalence of migraine headache in pediatric patients with epilepsy and the incidence of these two disorders in the family history.
Method:
A retrospective chart review was conducted on 475 patients with a primary diagnosis of epilepsy between January 2003 and June 2004. The patients were managed in a pediatric neurology outpatient clinic at a major teaching hospital. Cases were selected using the ICD-9-CM definition for epilepsy. Data collected included age, sex, headache, migraine, and family history.
Results:
The study revealed a higher prevalence of migraine in epilepsy patients (14.7%) than in the general population (2.7% to 11%). Only 4.7% had a family history of migraine, but 20.6% had a positive family history of epilepsy, supporting current ideas of the genetic etiology of some epilepsies.
Discussion:
This study specifically addressed epilepsy and migraine in children, but whenever a primary diagnosis is made, the potential for a coexisting disorder should be investigated.
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