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Three-dimensional Optical-resolution Photoacoustic Microscopy
Published on: May 3, 2011
A novel photoacoustic tomography based on a time-resolved technique and an acoustic lens imaging system
Yongheng He1, Zhilie Tang, Zhanxu Chen
1School of Physics and Telecommunication Engineering, South China Normal University, Guangzhou 510006, People's Republic of China.
Abstract:
A novel photoacoustic (PA) tomographic method, which is based on a time-resolved technique and an acoustic lens imaging system, is presented in this paper. A YAG laser operating at 532 nm with a 7 ns pulse width and 10 mJ optical pulse is employed as the excitation source to irradiate the tissue. PA signals generated from the tissue are imaged onto a multi-element linear array transducer with an acoustic lens. A 64 electronic switch is efficiently used for changing the parallel PA signals into a series. The proposed method directly provides PA images without any complex reconstruction algorithms. With the time-resolved technique, tomographic imaging can be achieved successfully. The results show that the images agree well with the original samples.

