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Updated: Aug 8, 2026

Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
[Effects of gastric bypass on erosive esophagitis in obese subjects]
Attila Csendes J1, Ana María Burgos L, Gladys Smok S
1Departamento de Cirugía, Hospital Clínico, Santiago, Chile. acsendes@med.uchile.cl
Background:
Obesity is an important risk for pathological gastroesophageal reflux.
Aim:
To assess the effects of gastric bypass on obese subjects with erosive esophagitis.
Patients And Methods:
Sixty two morbid obese subjects (aged 16 to 70 years, 41 females) with erosive esophagitis at the moment of surgery were studied. These patients were subjected to a gastric bypass with gastric resection. They were followed with upper gastrointestinal endoscopy every one year, looking for the presence of erosions or ulcers in the distal esophagus.
Results:
The mean follow up period was 21 months. Prior to surgery all patients had heartburn or regurgitation and at two years after surgery, 97% were asymptomatic. Esophagitis was found in 97 and 6.5% before and after surgery, respectively. Two patients had an esophageal ulcer, that healed on follow up endoscopy. There was a 72% reduction of overweight on late follow up.
Conclusions:
Gastric bypass is effective to control pathological gastroesophageal reflux in patients with morbid obesity.
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