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Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
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Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity

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Cisplatinum neuropathy with Lhermitte's sign

L Kumar1, V Kochupillai, P P Kotwal

  • 1Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi.

The Journal of the Association of Physicians of India
|September 1, 1991
PubMed

Abstract:

A case of cisplatinum induced neuropathy is reported because of its unusual presentation. Withdrawal of the drug resulted in improvement.

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Diabetic Neuropathy01:22

Diabetic Neuropathy

DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...

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