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Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
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Published on: April 23, 2021

[Isolated systolic arterial hypertension in elderly and senile patients]

N N Kipshidze, T G Zubiashvili

    Advances in Gerontology = Uspekhi Gerontologii
    |May 9, 2006
    PubMed

    Insights

    Systolic arterial pressure increases with age, a risk factor for major health issues. Combining Norvasc and Egilok effectively lowers blood pressure and improves heart function in elderly patients, with minimal side effects.

    Area of Science:

    • Geriatric Medicine
    • Cardiovascular Research
    • Pharmacology

    Background:

    • Systolic arterial pressure (SAP) increases with age.
    • Elevated SAP is a significant independent risk factor for cardiovascular, cerebral, and renal complications.
    • Geriatric populations often face challenges in managing hypertension due to comorbidities and increased risk of adverse drug reactions.

    Purpose of the Study:

    • To evaluate the efficacy and safety of a combined therapy using Norvasc and Egilok in geriatric patients.
    • To assess the impact of this combination on blood pressure control and left ventricular hypertrophy.
    • To determine the effect on systolic and diastolic cardiac function in the elderly.

    Main Methods:

    • A study involving geriatric patients with elevated systolic arterial pressure.
    • Administration of a combined therapy with Norvasc and Egilok in small therapeutic doses.
    • Monitoring of hypotensive effect, regression of left ventricular hypertrophy, and parameters of systolic and diastolic function.

    Main Results:

    • The combined use of Norvasc and Egilok achieved a stable hypotensive effect.
    • Significant regression of left ventricular hypertrophy was observed.
    • Improvement in both systolic and diastolic cardiac function parameters was noted.
    • Small therapeutic doses protected geriatric patients against adverse side effects.

    Conclusions:

    • Combined therapy with Norvasc and Egilok offers a stable hypotensive effect in geriatric patients.
    • This combination aids in the regression of left ventricular hypertrophy and improves cardiac function.
    • Low-dose combination therapy is a safe and effective strategy for managing hypertension in the elderly, minimizing side effects.

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