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Published on: June 14, 2019
[Cervical carcinoma in situ: a clinical and pathological analysis of 118 cases]
Jia-xin Yang1, Keng Shen, Jing-he Lang
1Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College and China Academy of Medical Sciences, Beijing 100730, China.
Objective:
To analyze the clinical characteristics and treatment of cervical carcinoma in situ.
Methods:
The clinical data of 118 patients with cervical carcinoma in situ (CIS), aged 38.8 (24-77), were retrospectively analyzed.
Results:
Cervical cytology showed that most of the lesions were cervical intraepithelial neoplasm (CINIII), high-grade squamous intraepithelial lesion (HSIL), or CIS. Most of the patients underwent colposcopic examination. All the patients underwent conization. 54% of the patients were given cold knife conization, and 46% of the patients received electric knife conization. 71 of the patients undergoing conization (60%) were followed-up. Another 40% received total hysterectomy and/or bilateral salpingo-oophorectomy. 17 cases were found pregnant after the conization. There were no differences in pathologically thorough resection and operational complication between the two surgery methods: cold knife conization and electric knife conization. Follow up study showed that conization had no effect on the subsequent pregnancy.
Conclusion:
Conization is necessary for the final diagnosis of cervical carcinoma in situ. Both cervical cytology and colposcopic examination are very important for screening of CINIII or CIS. For the young patients conization suffices, however, for the postmenopausal women or those unable to receive follow-up examination total hysterectomy and bilateral salpingo-oophorectomy should be considered.
