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[Supratentorial cavernous angiomas in children]
Mao-chun Wu1, Shi-qi Luo, Jian Xie
1Department of Neurosurgery, Beijing Tiantan Hospital, Beijing 100050, China.
Insights
Pediatric supratentorial cavernous angiomas treated with surgery show good seizure control and reduced re-bleeding. Shorter symptom duration before surgery improves seizure outcomes.
Area of Science:
- Neurology
- Neurosurgery
- Pediatric Neurosurgery
Background:
- Supratentorial cavernous angiomas are vascular malformations that can cause seizures and hemorrhage in children.
- Understanding their clinical presentation, treatment, and prognosis is crucial for effective management.
Purpose of the Study:
- To review the clinical features, treatment, and prognosis of pediatric supratentorial cavernous angiomas.
- To analyze the impact of epilepsy duration on surgical outcomes.
Main Methods:
- Retrospective review of clinical data from 25 pediatric patients with supratentorial cavernous angioma.
- Analysis of the relationship between preoperative epilepsy duration and postoperative seizure control.
Main Results:
- Surgery for supratentorial cavernous angiomas led to seizure freedom in all patients with less than one year of preoperative seizures.
- Half of patients with over one year of preoperative seizures achieved seizure freedom post-surgery.
- Surgery effectively prevented re-bleeding and new seizures in patients presenting with hemorrhage.
Conclusions:
- Craniotomy with lesionectomy is an effective treatment for supratentorial cavernous angiomas, achieving good seizure control and preventing re-bleeding.
- Shorter symptom duration prior to surgical intervention is associated with superior seizure control outcomes.
Objective:
To discuss the clinical features, treatment, and prognosis of supratentorial cavernous angiomas in children.
Methods:
The clinical data of 25 pediatric patients with supratentorial cavernous angioma, 17 boys and 6 girls, aged 9.6 (1-15), were reviewed retrospectively, and the relationship between the duration of epilepsy before surgery and prognosis was analyzed.
Results:
The 14 patients with preoperative seizures underwent surgery. All (8/8) of the patients suffering from preoperative seizures with an history of less than one year were seizure free after operation, while only half (3/6) of the patients with an history suffering from preoperative seizures with an history of more than one year were seizure free after operation. Ten of the 11 patients with hemorrhage and hemorrhage-related neurological symptoms as the initial symptoms underwent surgery, and no symptoms of re-bleeding and seizure occurred postoperatively.
Conclusion:
Craniotomy for lesionectomy results in good seizure control and re-bleeding avoidance. Better results with regard to seizure control are associated with shorter duration of symptoms before surgery.
