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Updated: Jul 11, 2026

Optical Mapping of Action Potentials and Calcium Transients in the Mouse Heart
Published on: September 13, 2011
CAMTA in cardiac hypertrophy
Robert J Schwartz1, Michael D Schneider
1The Institute of Biosciences and Technology, The Texas A&M University System Health Science Center, Houston, TX 77030, USA. rschwartz@ibt.tamhsc.edu
Abstract:
In this issue of Cell, the Calmodulin binding transcription activator 2 (CAMTA2), is shown by Song et al. (2006) to be an indispensable transcription coactivator for cardiac hypertrophy. CAMTA2 is activated by the dissociation of class II histone deacetylase 5 and promotes transcription of genes involved in cardiac hypertrophy through its interaction with Nkx2-5.
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