Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Three-Dimensional Force System:Problem Solving01:30

Three-Dimensional Force System:Problem Solving

1.4K
A three-dimensional force system refers to a scenario in which three forces act simultaneously in three different directions. This type of problem is commonly encountered in physics and engineering, where it is necessary to calculate the resultant force on the system, which can then be used to predict or analyze the behavior of the object or structure under consideration.
To solve a three-dimensional force system, first resolve each force into its respective scalar components. Do this using...
1.4K
Three-Dimensional Force System01:30

Three-Dimensional Force System

2.9K
In mechanical engineering, a three-dimensional force system is a system of forces acting in three dimensions, with forces applied along the x, y, and z coordinate axes. The three-dimensional force system is an important concept in mechanical engineering, as it allows engineers to understand and analyze the behavior of objects and structures in three dimensions. By understanding the forces acting on a system, engineers can design more efficient and effective mechanical systems that can withstand...
2.9K
Force and Potential Energy in Three Dimensions01:04

Force and Potential Energy in Three Dimensions

5.7K
Consider a particle moving under the action of a conservative force that has components along each coordinate axis. Each component of force is a function of the coordinates. The potential energy function U is also a function of all three spatial coordinates. Force in one dimension can be written as the negative ratio of potential energy change to the displacement along that coordinate. For minimal displacement, the ratios become derivatives. If a function has many variables, the derivative only...
5.7K
Depth Perception and Spatial Vision01:15

Depth Perception and Spatial Vision

2.2K
Depth perception is the ability to perceive objects three-dimensionally. It relies on two types of cues: binocular and monocular. Binocular cues depend on the combination of images from both eyes and how the eyes work together. Since the eyes are in slightly different positions, each eye captures a slightly different image. This disparity between images, known as binocular disparity, helps the brain interpret depth. When the brain compares these images, it determines the distance to an object.
2.2K
Three-Dimensional Analysis of Strain01:29

Three-Dimensional Analysis of Strain

650
Three-dimensional strain analysis is crucial for understanding how materials deform under stress, particularly in elastic, homogeneous materials. This method employs principal stress axes to simplify complex stress states into more understandable forms. Subjected to stress, a small cubic element within a material either expands or contracts along these axes, transforming into a rectangular parallelepiped. This transformation effectively illustrates the material's deformation. The principal...
650
Support Reactions in Three Dimensions01:27

Support Reactions in Three Dimensions

1.7K
Support reactions in three dimensions help maintain the stability and equilibrium of various structures and systems. These reactions prevent the system from translating and rotating, ensuring the design can withstand external forces and perform its intended function efficiently and safely. Some of the supports providing support reactions in three dimensions are discussed below:
Ball and Socket Joint is one of the supports allowing free rotation about any axis. This freedom of rotation is...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Activated T cell extracellular vesicle DNA transfer enhances antigen presentation and anti-tumor immunity.

Cancer cell·2026
Same author

Pancreatic Cancer Progression Involves Increased Lysyl Oxidase-Mediated Collagen Cross-Links as Part of the Desmoplastic Reaction.

Biochemistry·2025
Same author

A STAT3/integrin axis accelerates pancreatic cancer initiation and progression.

Cell reports·2025
Same author

Proteomic characterization of type I collagen N-terminal crosslinked peptides.

Matrix biology plus·2025
Same author

Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2.

Cell·2025
Same author

Unique structural configuration of EV-DNA primes Kupffer cell-mediated antitumor immunity to prevent metastatic progression.

Nature cancer·2024
Same journal

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions.

Cell·2026
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
See all related articles

Related Experiment Video

Updated: Feb 23, 2026

Author Spotlight: Insights into the Analysis of Human Interaction with 3D Virtual Objects
06:36

Author Spotlight: Insights into the Analysis of Human Interaction with 3D Virtual Objects

Published on: October 18, 2024

1.4K

Forcing the third dimension.

Nancy Boudreau1, Valerie Weaver

  • 1Surgical Research Laboratory, Department of Surgery, University of California, San Francisco, San Francisco, CA 94143, USA.

Cell
|May 9, 2006
PubMed
Summary
This summary is machine-generated.

Researchers discovered how matrix metalloproteinase MT1-MMP aids in the development of white adipose tissue. This finding advances understanding of tissue regeneration and the molecular basis of differentiation for therapeutic applications.

More Related Videos

Novel 3D/VR Interactive Environment for MD Simulations, Visualization and Analysis
11:29

Novel 3D/VR Interactive Environment for MD Simulations, Visualization and Analysis

Published on: December 18, 2014

12.3K
High-resolution, High-speed, Three-dimensional Video Imaging with Digital Fringe Projection Techniques
11:34

High-resolution, High-speed, Three-dimensional Video Imaging with Digital Fringe Projection Techniques

Published on: December 3, 2013

16.1K

Related Experiment Videos

Last Updated: Feb 23, 2026

Author Spotlight: Insights into the Analysis of Human Interaction with 3D Virtual Objects
06:36

Author Spotlight: Insights into the Analysis of Human Interaction with 3D Virtual Objects

Published on: October 18, 2024

1.4K
Novel 3D/VR Interactive Environment for MD Simulations, Visualization and Analysis
11:29

Novel 3D/VR Interactive Environment for MD Simulations, Visualization and Analysis

Published on: December 18, 2014

12.3K
High-resolution, High-speed, Three-dimensional Video Imaging with Digital Fringe Projection Techniques
11:34

High-resolution, High-speed, Three-dimensional Video Imaging with Digital Fringe Projection Techniques

Published on: December 3, 2013

16.1K

Area of Science:

  • Biomedical research
  • Tissue engineering
  • Molecular biology

Background:

  • Biomedical research aims to develop surrogate tissues for regenerative medicine.
  • Understanding tissue-specific differentiation is crucial for tissue engineering.
  • The extracellular matrix plays a role in tissue development.

Discussion:

  • Chun et al. (2006) investigated the molecular mechanisms underlying white adipose tissue development in mice.
  • The study focused on the role of extracellular matrix remodeling.
  • Matrix metalloproteinase MT1-MMP was identified as a key enzyme.

Key Insights:

  • Matrix metalloproteinase MT1-MMP facilitates the remodeling of the extracellular matrix.
  • This remodeling is essential for the three-dimensional development of white adipose tissue.
  • The findings provide molecular insights into tissue-specific differentiation.

Outlook:

  • This research contributes to the goal of constructing surrogate tissues for replacement therapy.
  • Understanding MT1-MMP's role can inform strategies for promoting tissue regeneration.
  • Further studies may explore therapeutic applications of targeting extracellular matrix remodeling.