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Related Experiment Videos

Central corneal thickness in children: stability over time.

Kelly W Muir1, Lois Duncan, Laura B Enyedi

  • 1Duke University Eye Center, Durham, NC 27710, USA.

American Journal of Ophthalmology
|May 9, 2006
PubMed
Summary

Central corneal thickness (CCT) in children aged 3-14 years remains stable over one to two years. This study evaluated CCT changes in pediatric patients, including those with glaucoma.

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Area of Science:

  • Ophthalmology
  • Pediatric eye care
  • Corneal imaging

Background:

  • Central corneal thickness (CCT) is a critical parameter in ophthalmology.
  • Understanding CCT stability in pediatric populations is essential for accurate diagnosis and management.
  • Pediatric glaucoma management requires knowledge of normative CCT values.

Purpose of the Study:

  • To evaluate changes in central corneal thickness (CCT) over time in children.
  • To assess CCT stability in pediatric patients aged 3 to 14 years.
  • To investigate potential CCT variations in children with and without glaucoma.

Main Methods:

  • Prospective observational case series.
  • Ultrasonic pachymetry used to measure CCT in 69 eyes of 38 subjects (ages 3-14).

Related Experiment Videos

  • Subjects included patients with and without glaucoma, with measurements taken over a one- to two-year interval.

    • Main Results:

    • No statistically significant changes in CCT were observed over the study period.
    • Mean CCT change in eyes without glaucoma medication was -1.9 microm.
    • Mean CCT change in eyes on stable glaucoma medication was +8.1 microm, and -3.8 microm with therapy changes.

    Conclusions:

    • Central corneal thickness (CCT) in children aged 3 to 14 years appears stable over one- to two-year intervals.
    • These findings suggest CCT is a reliable measurement in pediatric ophthalmology.
    • Further research may explore long-term CCT trends in pediatric glaucoma patients.