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Published on: August 14, 2019
Cost-effectiveness of influenza vaccination of healthy children
Heini Salo1, Terhi Kilpi, Harri Sintonen
1Department of Vaccines, National Public Health Institute, KTL, 00300 Helsinki, Finland.
Insights
Influenza vaccination for children aged 6 months to 13 years is cost-saving in Finland. This study shows that vaccinating children against influenza provides economic benefits for healthcare systems and society.
Area of Science:
- Public Health
- Health Economics
- Vaccinology
Background:
- Influenza vaccination is recommended for young children in the US and Canada due to high hospitalization rates.
- Few other countries have adopted similar policies for pediatric influenza vaccination.
- The cost-effectiveness of pediatric influenza vaccination remains under-established globally.
Purpose of the Study:
- To assess the cost-effectiveness of influenza vaccination for children aged 6 months to 13 years in Finland.
- To analyze the economic impact of influenza on children and their families from both healthcare provider and societal perspectives.
Main Methods:
- A decision analysis model was utilized to evaluate cost-effectiveness.
- The model incorporated comprehensive clinical data on influenza infections, hospital records, and national registers.
- Analyses were conducted from both healthcare provider and societal viewpoints.
Main Results:
- Influenza vaccination demonstrated cost savings across all analyzed programs for children up to 13 years old.
- Investing €1.7 million in vaccinating children under 5 yielded €2.7 million in healthcare savings.
- Savings per vaccinated child ranged from €5.7 to €12.6, even with 60% vaccine efficacy.
Conclusions:
- Influenza vaccination is a cost-saving strategy for all children up to 13 years of age in Finland.
- The findings support reconsideration of current influenza vaccine recommendations in countries worldwide.
- Pediatric influenza vaccination offers significant economic benefits, justifying broader policy adoption.
Abstract:
Influenza vaccination of children 6-23 months of age is recommended in the United States and Canada because of high rates of influenza-associated hospitalisations, but few other countries have adopted similar policies. Most children with influenza are treated in the primary care setting, and the cost-effectiveness of influenza vaccination of children has not been fully established. We used a decision analysis model to assess the cost-effectiveness of influenza vaccination of children 6 months to 13 years of age in Finland. The analyses were based on comprehensive clinical data on virologically confirmed influenza infections, hospital medical records, and national registers. We estimated the impact of influenza on outpatient and hospitalised children and their families, and performed the analyses from the health care provider and societal perspective. Influenza vaccination resulted in savings in all programs including children
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