A multi-method assessment of treatment adherence for children with cystic fibrosis
Avani C Modi1, Crystal S Lim, Nami Yu
1Cincinnati Children's Hospital Medical Center, Division of Behavioral Medicine and Clinical Psychology, 3333 Burnet Avenue, MLC-3015, Cincinnati, OH 45229, United States. avani.modi@cchmc.org <avani.modi@cchmc.org>
Insights
Pediatric adherence to chronic condition treatments is low, around 50%. For children with cystic fibrosis (CF), objective adherence measures reveal rates below 50%, highlighting a need for better interventions.
Area of Science:
- Pediatric adherence research
- Chronic disease management
- Cystic Fibrosis treatment
Background:
- Adherence to treatments for chronic pediatric conditions averages approximately 50%.
- Children with cystic fibrosis (CF) face challenges in adhering to complex treatment regimens.
Purpose of the Study:
- To assess adherence rates in children with cystic fibrosis (CF) using four distinct measurement methods.
- To compare the effectiveness of different adherence assessment tools in a pediatric CF population.
Main Methods:
- A study involving 37 children with CF (ages 6-13) and their caregivers.
- Utilized parent/child self-reports, diary data, pharmacy refill history, and electronic monitoring for adherence assessment.
Main Results:
- Adherence rates varied significantly based on the treatment component and measurement method used.
- Objective measures indicated overall adherence below 50% for children with CF.
- Adherence to enzyme medications, measured by electronic and diary methods, ranged from 27% to 46%.
Conclusions:
- A multi-method approach provides comprehensive insights into adherence across different treatment types for CF.
- Accurate measurement of treatment adherence is crucial for developing targeted interventions.
- Findings underscore the need for improved strategies to enhance pediatric adherence in CF management.
Background:
Adherence rates for chronic pediatric conditions are approximately 50%. The primary objective of the study was to assess rates of adherence using four different measurement methods for children with cystic fibrosis (CF).
Methods:
Participants included 37 children with CF between 6 and 13 years of age and their primary caregivers. Adherence measures included parent and child self-reports, diary data, pharmacy refill history, and electronic monitors.
Results:
Results suggested that rates of adherence varied by treatment component and across measurement methods. However, when examining more objective measures, rates of overall adherence were below 50% for children with CF, indicating generally poor adherence to the treatment regimen. For example, rates of adherence to enzyme medications, using electronic and diary measures, ranged from 27% to 46%.
Conclusions:
The multi-method measurement approach provided unique information regarding rates of adherence for each disease condition by type of treatment component. Accurately measuring rates of treatment adherence for children with CF is an important step in developing effective interventions to influence these behaviors.
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