Related Experiment Video
Updated: Jul 30, 2026
Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
Published on: July 4, 2007
Neuropsychiatric manifestations systemic lupus erythematosus: a study from South India
M Robert1, R Sunitha, N K Thulaseedharan
1Department of Neurology, Medical College Hospital, Trivandrum, Kerala, India. robert_mathew@hotmail.com
Context:
Neuropsychiatric systemic lupus erythematosus (NPSLE) has varied manifestations.
Aims:
To study the pattern of neuropsychiatric (NP) involvement in systemic lupus erythematosus (SLE).
Settings And Design:
Hospital based cross sectional and retrospective study.
Patients And Methods:
Patients admitted with a diagnosis of SLE, during a period of 16 months, were evaluated and any NP syndrome present classified as per the American College of Rheumatology (ACR) nomenclature.
Statistical Analysis:
SPSS software Version 10 was used for descriptive analysis and correlative study.
Results:
Out of 50 patients with SLE, all the patients with NPSLE [39 (78%)] were females, mean age 25.66 years (range: 11-44). The commonest manifestation was headache [20 (55.6%)]. Seizures were seen in 8 (20.51%) and psychosis in 6 (16.2%). Fine distal tremor was seen in 8 (20.51%) of patients.
Conclusions:
Headache is a frequent NP syndrome. Fine distal tremor is a syndrome not included in ACR classification but seen is 20% of our patients with NPSLE.
