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Diabetic foot infection
Nidal A Younes1, Faris G Bakri
1Department of Surgery, Faculty of Medicine, University of Jordan, PO Box 13024, Amman 11942, Jordan. niyounes@ju.edu.jo
Abstract:
Diabetic foot infection DFI is simply defined as suspected or documented infection of the tissues that comprise the foot of a diabetic patient. Diabetic foot infection is often caused by introduction of an infection into the otherwise sterile soft tissues of the foot through a minor skin break down. Diabetic foot infection may be mild usually restricted to the uppermost layers of the skin, moderate extending down to the soft tissues of the foot or severe infection associated with systemic toxicity or metabolic instability. The paper reviews the types of DFI, pathophysiology, microbiology of DFI, relevant anatomy of the foot, clinical evaluation, measures of severity of DFI, the role of radiological investigations, and the role of early surgical intervention in the prevention of progressive foot infection and limb salvage. It is concluded that the diagnosis of DFI should be suspected at an early stage based on the presence of local signs of inflammation with or without systemic signs of toxicity or metabolic instability. Optimal treatment of DFI requires a multimodality approach directed at controlling hyperglycemia, administration of systemic antibiotics, and local wound management to prevent the spread and dissemination of infection.
Insights
Diabetic foot infection (DFI) requires early suspicion based on inflammation signs. Optimal DFI treatment involves controlling blood sugar, antibiotics, and local wound care to prevent infection spread and save limbs.
Area of Science:
- Podiatry
- Infectious Diseases
- Endocrinology
Background:
- Diabetic foot infection (DFI) is a common complication in diabetic patients.
- DFI often originates from minor skin breaches, leading to soft tissue infections.
- Infections range from mild to severe, potentially causing systemic toxicity.
Purpose of the Study:
- To review the types, pathophysiology, and microbiology of diabetic foot infections.
- To outline clinical evaluation, severity assessment, and the role of imaging in DFI.
- To emphasize early surgical intervention for limb salvage and infection prevention.
Main Methods:
- Literature review of DFI types, pathophysiology, microbiology, and anatomy.
- Analysis of clinical evaluation, severity grading, and radiological investigations.
- Examination of early surgical intervention's role in DFI management.
Main Results:
- DFI diagnosis should be suspected early based on local inflammation and systemic signs.
- Severity assessment guides treatment strategies.
- Early intervention is crucial for preventing infection progression.
Conclusions:
- DFI diagnosis requires early suspicion using clinical signs.
- Optimal DFI management necessitates a multimodal approach.
- Controlling hyperglycemia, systemic antibiotics, and local wound care are key to successful DFI treatment and limb salvage.
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