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Updated: Aug 8, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Targets and endpoints in ablation therapy for atrial fibrillation in the light of pathophysiological mechanisms
Marcoen F Scholten1, Andrew S Thornton, Joris M Mekel
1Clinical Electrophysiology Unit, Department of Cardiology, Thoraxcentre, Erasmus MC, Dr Molewaterplein 40., 3015 GD, Rotterdam, The Netherlands. m.f.scholten@erasmusmc.nl
Abstract:
Atrial fibrillation (AF), an important public health problem is a complex and multifactorial arrhythmia. Non-pharmacological treatment for symptomatic patients is of increasing importance. The different catheter ablation techniques in AF treatment developed during recent years, all based on different pathophysiological insights, are discussed. The non-standardized use of different follow-up methods after ablation make interpretation and comparison of results difficult.
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