Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thromboembolic disease in hip replacement surgery.

E Salvati1, A Gonzales Della Valle, A Zoppi

  • 1Hip and Knee Service, Hospital for Special Surgery, New York, USA.

La Chirurgia Degli Organi Di Movimento
|May 10, 2006
PubMed
Summary

Total hip replacement poses fatal risks of thromboembolic complications. Advances in understanding disease mechanisms and perioperative prophylaxis have significantly reduced these risks over 30 years.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-World Efficacy and Safety of Gemtuzumab Ozogamycin (GO) and 3 + 7 regimen in fit newly diagnosed Acute Myeloid Leukemia (AML) patients. A Retrospective multicenter study of "Rete Ematologica Pugliese" (REP).

Leukemia research reports·2025
Same author

Polydactyly and syndactyly linked to GLI3 and TBX5 mutations: A pediatric case report.

Global medical genetics·2025
Same author

Exposure to obinutuzumab does not affect outcomes of SARS-CoV-2 infection in vaccinated patients with newly diagnosed advanced-stage follicular lymphoma.

British journal of haematology·2024
Same author

Radioimmunotherapy versus autologous hematopoietic stem cell transplantation in relapsed/refractory follicular lymphoma: a Fondazione Italiana Linfomi multicenter, randomized, phase III trial.

Annals of oncology : official journal of the European Society for Medical Oncology·2023
Same author

PARP1 allows proper telomere replication through TRF1 poly (ADP-ribosyl)ation and helicase recruitment.

Communications biology·2023
Same author

Isolated radial tears of the lateral meniscus midbody: a case series of professional athletes treated with outside-in repair.

Musculoskeletal surgery·2022

Area of Science:

  • Orthopedic Surgery
  • Vascular Medicine
  • Thromboembolic Disease

Background:

  • Total hip replacement (THR) surgery is associated with potentially fatal thromboembolic complications.
  • Significant advancements in understanding thromboembolic disease pathogenesis and perioperative prophylaxis have occurred over the past three decades.
  • Risk reduction strategies are crucial for patient safety in THR.

Purpose of the Study:

  • To review and discuss essential medical and surgical preventive measures for thromboembolic complications in THR.
  • To highlight the importance of proactive, perioperative prophylaxis.
  • To emphasize the obsolescence of post-operative prophylaxis decision-making.

Main Methods:

  • Review of current medical and surgical literature on thromboembolic prophylaxis in THR.

Related Experiment Videos

  • Analysis of physiopathogenetic mechanisms of thromboembolic disease.
  • Synthesis of best practices for perioperative preventive strategies.
  • Main Results:

    • Perioperative prophylaxis strategies have evolved significantly, leading to reduced complication rates.
    • A comprehensive approach involving measures before, during, and immediately after surgery is most effective.
    • Current evidence supports the necessity of pre-emptive prophylaxis.

    Conclusions:

    • Proactive and comprehensive perioperative thromboembolic prophylaxis is essential for safe total hip replacement.
    • The traditional approach of delaying prophylaxis decisions until after surgery is no longer considered optimal.
    • Continued research and adherence to evidence-based guidelines are vital for minimizing risks.