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Updated: Aug 7, 2026

Quantification of Orofacial Phenotypes in Xenopus
Published on: November 6, 2014
Digital surface photogrammetry for anthropometric analysis of the cleft infant face
Michael Krimmel1, Susanne Kluba, Margit Bacher
1Department of Oral and Maxillofacial Surgery, University Hospital Tübingen, Germany. Michael.Krimmel@med.uni-tuebingen.de
Objective:
To analyze the three-dimensional morphology of the cleft infant face with digital surface photogrammetry.
Design:
Fifty plaster casts of unoperated infants with cleft lip and palate were imaged three-dimensionally with digital surface photogrammetry. Twenty-one standard craniofacial measurements were taken. The plaster casts were divided into 4 groups with unilateral, bilateral, complete, and incomplete clefts of the lip and palate. The measurements were compared with standard values for healthy infants.
Results:
Significant differences (p < .0025) were found for the alar base width (33% to 55%), the alar base root width (59% to 103%), the width of the nose (7% to 25%), the length of the alar wing (18% to 25%), and the intercanthal (6% to 17%) and biocular (4% to 12%) width, depending on the cleft type. The vertical dimensions of the nose and the upper lip did not differ significantly from the controls.
Conclusion:
This study describes preliminary data on the cleft infant facial deformity. The obtained results were mainly in agreement with data in the limited literature. Three-dimensional photogrammetry has proven to be reliable and can be applied more readily to potentially uncooperative patients.
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