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Published on: November 4, 2025

Mirizzi syndrome: history, present and future development

Eric C Lai1, Wan Yee Lau

  • 1Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.

ANZ Journal of Surgery
|May 10, 2006
PubMed
Abstract

Insights

Mirizzi syndrome, a complication of gallstones, increases bile duct injury risk during gallbladder removal. High suspicion and open surgery are recommended due to limited laparoscopic data and high conversion rates.

Area of Science:

  • Gastroenterology
  • Hepatobiliary Surgery

Background:

  • Mirizzi syndrome affects 0.3-3% of patients undergoing cholecystectomy.
  • Anatomical distortion and cholecystocholedochal fistula increase bile duct injury risk.

Purpose of the Study:

  • To review the diagnosis and surgical management of Mirizzi syndrome.
  • To evaluate outcomes of different surgical approaches.

Main Methods:

  • A systematic literature search was conducted using Medline (1974-2004).
  • References from key articles were manually reviewed.

Main Results:

  • Preoperative diagnosis rates ranged from 8-62.5%.
  • Open surgery demonstrated good short- and long-term outcomes.
  • Laparoscopic treatment data was limited, with high conversion rates and variable bile duct injury (0-22.2%).

Conclusions:

  • High clinical suspicion is crucial for preoperative/intraoperative diagnosis and surgical planning.
  • Open surgery remains the gold standard for Mirizzi syndrome.
  • Mirizzi syndrome should be considered a contraindication for laparoscopic surgery.

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