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Management of chronic hepatitis B virus infection: current perspectives for the nurse practitioner

Robert Perrillo1

  • 1Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, New Orleans, Louisiana 70121, USA. rperrillo@ochsner.org

Journal of the American Academy of Nurse Practitioners
|May 10, 2006
PubMed

Insights

Effective management of chronic hepatitis B virus (HBV) infection involves prevention, screening, and antiviral therapies like nucleoside analogues and interferons. Careful patient assessment guides treatment selection for better outcomes.

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Viral Hepatitis

Background:

  • Chronic hepatitis B virus (HBV) infection is a significant global health concern.
  • It is a leading cause of liver cirrhosis, hepatocellular carcinoma, and liver-related mortality worldwide.

Purpose of the Study:

  • To provide a comprehensive overview of the clinical management of chronic HBV infection.
  • To emphasize recent advancements in the natural history, prevention, and antiviral therapy of HBV.

Main Methods:

  • Literature review of studies from the National Library of Medicine.
  • Focus on recent research concerning chronic HBV infection.

Main Results:

  • Chronic HBV infection contributes to severe liver disease and mortality globally.
  • Prevention strategies, cancer screening for carriers, and treatment are crucial for managing HBV.

Conclusions:

  • Preventing and treating chronic HBV infection is achievable.
  • Nucleoside analogues and interferons are available therapies with distinct advantages and disadvantages.
  • Treatment decisions require consideration of biochemical, histological, and virological data, alongside practical factors.
Abstract

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