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Updated: Aug 6, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 12, 2014
[Epidemiological aspects of cervical neoplasms]
1Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina, Universidade Federal de Minas Gerais-Belo Horizonte, Brasil.
Abstract:
A review concerning the epidemiological issues relating to cervical cancer, one of the most frequent in the women of developing countries, was undertaken in Brazil, the incidence rate varies from 23.7/100,000 in Porto Alegre to 83.2/100,000 in Recife. In the United States, the 1978 incidence rate was 6.8/100,000 in white women and 14.7/100,000 among black women. Several studies have suggested the hypotheses that cervical cancer could be related to some venereal agent. The evidences have shown the human papillomavirus (HPV) to be the main etiological agent. Several studies on the validity of such a hypotheses were realized and it became clear that there does in fact exist a relationship between the HPV and cervical cancer. Finally, the better known risk factors, such as sexual behaviour, smoking and the contraception were studied in the light of the various etiological hypotheses.
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