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A population-based study of the incidence and prognosis of lacunar stroke

S Sacco1, C Marini, R Totaro

  • 1Department of Neurology, University of L'Aquila, Italy.

Neurology
|May 10, 2006
PubMed

Insights

Lacunar stroke incidence was 33.0 per 100,000 annually. While short-term risks were lower than nonlacunar stroke, long-term death and recurrence risks became similar.

Area of Science:

  • Neurology
  • Epidemiology

Background:

  • Lacunar stroke is a subtype of ischemic stroke.
  • Understanding its incidence and prognosis is crucial for public health.

Purpose of the Study:

  • To determine the incidence and prognosis of lacunar stroke.
  • To compare lacunar stroke outcomes with nonlacunar stroke.

Main Methods:

  • Prospective, population-based study.
  • Inclusion of first-ever strokes from 1994-1998.
  • Assessment of incidence, risk factors, mortality, and recurrence.

Main Results:

  • Annual incidence of first-ever lacunar stroke was 33.0/100,000.
  • Lacunar stroke patients had higher rates of smoking and hypercholesterolemia, and lower rates of atrial fibrillation.
  • 30-day and 1-year case-fatality rates for lacunar stroke were 4.3% and 13.0%, respectively.
  • First-year stroke recurrence was lower for lacunar stroke (2.83%) compared to nonlacunar stroke (5.10%), with similar rates thereafter.

Conclusions:

  • Short-term vascular events were more frequent in nonlacunar stroke.
  • Long-term risks of death and stroke recurrence were similar between lacunar and nonlacunar stroke patients.
Abstract

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