Related Experiment Video
Updated: Aug 8, 2026

A Rat Model of EcoHIV Brain Infection
Published on: January 21, 2021
Variable benefit in neuropsychological function in HIV-infected HAART-treated patients
Lucette A J Cysique1, Paul Maruff, Bruce J Brew
1Faculty of Medicine, St. Vincent's Clinical School, University of New South Wales, Sydney, Australia. lcysique@ucsd.edu
Abstract:
The authors examined cognitive performance change in 101 individuals with advanced HIV infection on highly active antiretroviral therapy (HAART), using standard neuropsychological testing in three visits, over a 27-month-period. Cognitive performance stabilized in a majority of HIV+ participants over time. A neuroactive HAART regimen was associated with neuropsychological improvement. Decline occurred in a minority with lower nadir CD4. The current CD4 count and plasma viral load were not associated with cognitive change.
Related Concept Videos
Retrovirus Life Cycles
Cryptococcal Meningitis

