Related Experiment Video
Updated: Jul 18, 2026

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
Published on: July 14, 2016
Haemophilia and ageing.
1Ronald Sawers Haemophilia Centre, Melbourne, Australia. A.Street@alfred.org.au
Older men with haemophilia face unique ageing challenges, including falls and cardiovascular issues, alongside HIV/HCV and arthritis complications. Proactive wellness programs are crucial for early disease detection and managing the physical and psychological impacts of ageing.
Area of Science:
- Geriatrics
- Hematology
- Internal Medicine
Background:
- Men with haemophilia (PWH) experience HIV/HCV infections and premature arthritis.
- PWH also face common ageing issues like genitourinary and arterial diseases.
- Progressive arthritis and declining fitness can lead to loss of independence and psychological distress.
Purpose of the Study:
- To address falls, cardiovascular problems, and other ageing-related health issues in older men with haemophilia.
- To highlight the need for increased awareness and proactive management strategies for ageing PWH.
- To advocate for the development of 'wellness' programs tailored to the specific needs of this population.
Main Methods:
- This paper reviews existing literature on ageing issues in men with haemophilia.
- It specifically addresses falls, their causes and consequences, and cardiovascular problems.
- The paper emphasizes the need for a comprehensive approach to managing health in this demographic.
Main Results:
- Limited literature exists on common ageing problems in men with haemophilia.
- Haemophilia does not confer protection against arterial disease.
- Falls and cardiovascular issues are significant concerns impacting independence and quality of life.
Conclusions:
- Older men with haemophilia encounter complex health challenges, including ageing-related conditions and complications from their disorder.
- Haemophilia centers often manage all health issues, but primary care physician involvement is sometimes limited.
- Developing targeted 'wellness' programs is essential for early disease identification and prevention of adverse ageing impacts.
Related Concept Videos
The Effect of Aging on Tissues
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Disorders of Hemostasis
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Pharmacodynamics in Geriatric Patients: Effects of Age

