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Effects of buspirone on the immunosuppressive response to stress in mice
M Freire-Garabal1, A Belmonte, J Suárez-Quintanilla
1Department of Pharmacology, School of Medicine, University of Santiago de Compostela, Spain.
Archives Internationales De Pharmacodynamie Et De Therapie
|November 1, 1991
Abstract:
Mice exposed to a chronic auditory stressor and treated with buspirone (1 mg/kg/day) showed a reduction in stress-induced suppression of thymus and spleen cellularity, and in peripheral T-lymphocyte population. The blastic response of spleen lymphoid cells was also assessed and buspirone was found to partially suppress the inhibitory effect of stress.