Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[eIF4E and developmental decisions: when translation drives the development].

Nathalie Oulhen1, Patrick Cormier

  • 1Station Biologique de Roscoff, Cycle Cellulaire et Développement, Unité Mer et Santé (UMR 7150), Université Pierre-et-Marie Curie (EI 37), Centre National de la Recherche Scientifique, Institut National des Sciences de l'Univers, Roscoff, France.

Medecine Sciences : M/S
|May 12, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trans-Phylum Single Cell Orthology Reveals Conserved Ovarian Cell States Between Sea Urchin and Human.

Genome biology and evolution·2026
Same author

The activation of the mTOR pathway supports lysosome biogenesis in the sea urchin embryo.

Development (Cambridge, England)·2026
Same author

Single cell RNA seq of the major cell types in the larva of the sea star, Patiria miniata.

Developmental dynamics : an official publication of the American Association of Anatomists·2025
Same author

Collagen processing is essential for germ cell identity.

Biology open·2025
Same author

A collagenous extracellular matrix regulates germline gene expression in the sea star embryo.

Scientific reports·2025
Same author

A transcriptomic atlas of adult tissues of the sea urchin Lytechinus variegatus identifies early transitions in gonadogenesis.

Developmental biology·2025
Same journal

[CREPT: An ally of immunotherapy for the fight against non-small-cell lung cancers].

Medecine sciences : M/S·2026
Same journal

[A new regulatory mechanism of HIF-1α: the ROS-ATM-CHK2 axis at the core of tumor angiogenesis].

Medecine sciences : M/S·2026
Same journal

[Vibrio-host interactions: from the environmental niche to virulence].

Medecine sciences : M/S·2026
Same journal

[RcsF, hyperconnected sentinel of the bacterial envelope].

Medecine sciences : M/S·2026
Same journal

[Single-cell RNA-sequencing: shattering the clone myth].

Medecine sciences : M/S·2026
Same journal

[No, Physarum blobs do not have 720 sexes!]

Medecine sciences : M/S·2026
See all related articles

mRNA translation regulation is crucial for embryonic development. The eukaryotic initiation factor 4E (eIF4E) and its partners are key regulators of protein production during embryogenesis.

Area of Science:

  • Molecular Biology
  • Developmental Biology
  • Gene Expression Regulation

Context:

  • mRNA translation is a critical control point in gene expression.
  • Precise protein synthesis is essential for successful embryonic development, including gametogenesis, fertilization, and axis formation.
  • The eukaryotic initiation factor 4E (eIF4E) is a central regulator of cap-dependent translation.

Purpose:

  • To review recent advancements in understanding the role of translational regulators in development.
  • To highlight the significance of eIF4E and its interacting partners in developmental decisions.

Summary:

  • This review focuses on the importance of mRNA translation regulation during embryonic development.
  • It details the critical role of the eukaryotic initiation factor 4E (eIF4E) in cap-dependent translation.

Related Experiment Videos

  • Recent findings on eIF4E and its partners in governing developmental processes are discussed.

    • Impact:

    • Provides insights into the molecular mechanisms underlying developmental processes.
    • Identifies eIF4E as a key player in regulating protein synthesis for embryonic development.
    • Offers a foundation for future research into translational control in developmental biology.