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Related Experiment Video

Updated: Jul 24, 2026

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis

Published on: October 2, 2020

Blood pressure instability during hemodialysis.

D W Landry¹, J A Oliver

¹Department of Medicine, Columbia University, New York, NY 10027, USA. DWL1@columbia.edu

Kidney International

|May 12, 2006

Summary

Patients on hemodialysis often have hypertension, but can experience hypotension due to impaired baroreflex function. Studying these blood pressure changes offers insights into arterial pressure regulation in end-stage renal disease (ESRD).

Area of Science:

Nephrology
Cardiovascular Physiology

Background:

Most end-stage renal disease (ESRD) patients on hemodialysis suffer from chronic hypertension.
Hypotension is a common complication during hemodialysis, potentially linked to baroreflex dysfunction.

Discussion:

Paradoxical increases in blood pressure can also occur during hemodialysis.
Investigating these arterial pressure abnormalities provides valuable data on ESRD cardiovascular regulation.

Key Insights:

Hemodialysis can cause both hypotension and hypertension in ESRD patients.
Baroreflex function impairment is a likely cause of intradialytic hypotension.

Outlook:

Further research into intradialytic blood pressure fluctuations can enhance patient management.

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Understanding arterial pressure regulation in ESRD may lead to improved therapeutic strategies.