Related Experiment Video
Updated: Aug 8, 2026

Isolation, Processing and Analysis of Murine Gingival Cells
Published on: July 2, 2013
Morphoclinical aspects of the human paraprostethic gingival mucosa
Monica Scrieciu1, Mihaela Niculescu, Veronica Mercuţ
1Department of Removable Prosthodontics, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, Romania. scrieciu_monica@yahoo.com
Abstract:
The multiple and various changes that the human gingival mucosa undergoes when coming into contact with a denture, require a histopathological study correlated with that of clinical manifestations. The highlighting of the histological lesions of the prosthetic field's mucosa is extremely important in the study concerning the tolerance of the oral cavity tissues towards the materials of dentures, because it has been observed that different materials can cause the same type of clinical changes. The clinical research has been carried out having as a basis a group of patients, carriers of fixed dentures made of different materials, the study method consisting in their clinical evaluation. The investigation of microscopic preparations, obtained through drawing mucosa from those patients under study, has been made by using both usual colorations for an overall examination of the tissue architecture, as well as special colorations for pointing out certain structures. The results of the investigation have made clear the fact that the clinical changes of the prosthetic field's mucosa can be adaptable to the denture or can react pathologically to the various possibilities of denture aggression. The histopathological picture of the paraprosthetic mucosa lesions is polymorphous due to the morphofunctional complexity as well as to the reacting capacity of the oral mucosa when interfering with a fixed denture.

