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Updated: Aug 8, 2026
08:49
Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
Published on: May 11, 2018
[Ventricular assist system]
1Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|May 13, 2006
Summary
Ventricular assist systems (VAS) offer a vital therapy for severe heart failure patients, serving as a bridge to recovery, transplantation, or destination therapy. This review explores the current use and future of VAS in Japan.
Area of Science:
- Cardiovascular Medicine
- Medical Devices
- Regenerative Medicine
Context:
- Severe end-stage heart failure presents significant therapeutic challenges.
- Existing medical treatments are insufficient for patients with cardiogenic shock or progressive cardiac deterioration.
- Brain-dead donor organ shortage limits heart transplantation options.
Purpose:
- To review the current applications of Ventricular Assist Systems (VAS) for end-stage heart failure in Japan.
- To discuss the expanding role of VAS as destination therapy.
- To outline future directions for VAS therapy in the Japanese context.
Summary:
- Ventricular Assist Systems (VAS) are a crucial option for patients with end-stage heart failure, cardiogenic shock, or progressive cardiac deterioration.
- VAS functions as a bridge to recovery or heart transplantation.
- Due to donor organ scarcity, VAS is increasingly utilized as destination therapy, an alternative to transplantation.
Impact:
- VAS implantation offers a life-saving strategy for patients ineligible for or awaiting heart transplantation.
- The expanding role of VAS as destination therapy addresses the critical shortage of donor organs.
- This review provides insights into the evolving landscape and future potential of VAS therapy in Japan.
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