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Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
10:49

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus

Published on: January 28, 2019

[Epidemiology of rotavirus infections in the Federal District, Brazil]

J M Teixeira, R B de Figueiredo, H M dos Santos

    Revista Da Sociedade Brasileira De Medicina Tropical
    |October 1, 1991
    PubMed

    Insights

    Rotavirus, a common cause of diarrhea in young children, was detected in 20.27% of fecal samples. Subgroup II rotaviruses were most prevalent, particularly in children aged 6-24 months.

    Area of Science:

    • Pediatric Infectious Diseases
    • Virology
    • Gastroenterology

    Context:

    • Acute diarrhea is a significant health concern in infants and young children.
    • Rotavirus is a leading viral pathogen responsible for severe gastroenteritis in this age group.
    • Understanding rotavirus prevalence and characteristics is crucial for public health interventions.

    Purpose:

    • To determine the prevalence of rotavirus infection in young children with acute diarrhea.
    • To characterize the rotavirus strains detected using polyacrylamide gel electrophoresis (PAGE).
    • To investigate the association of rotavirus infection with age and season.

    Summary:

    • Rotavirus testing on 607 fecal samples from children aged 0-6 years with acute diarrhea revealed a prevalence of 20.27%.
    • Polyacrylamide gel electrophoresis (PAGE) analysis identified rotaviruses in 123 samples, with 87% classified as subgroup II (long profile).
    • Infection was most common in children aged 6-24 months (73.98%), with higher detection rates during the dry season (34.48%) and coldest months (June-July).

    Impact:

    • This study provides valuable epidemiological data on rotavirus in a specific pediatric population.
    • Findings highlight the importance of age and seasonal factors in rotavirus transmission.
    • Results can inform vaccination strategies and public health policies for rotavirus prevention and control.

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