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Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
05:53

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Published on: July 6, 2013

Cytomegalovirus: a cause of colonic stricture in a premature infant

Anjali Shetty1, Rosemary Barnes, Ed Lazda

  • 1University Hospital of Wales, Microbiology, Heath Park, Cardiff, United Kingdom. anjalishettyuk@yahoo.co.uk

The Journal of Infection
|May 13, 2006
PubMed

Insights

Cytomegalovirus infection in infants can cause severe bowel obstruction. This rare neonatal condition requires consideration by clinicians to prevent serious complications.

Area of Science:

  • Neonatalogy
  • Gastroenterology
  • Virology

Background:

  • Cytomegalovirus (CMV) infections are uncommon in neonates.
  • Gastrointestinal involvement in neonatal CMV is rare.

Observation:

  • A 27-week-old infant presented with symptoms of bowel obstruction upon initiation of full enteral feeds.
  • Surgical exploration revealed colonic strictures in the ascending and proximal transverse colon.
  • Histological examination of the resected colon showed Cytomegalovirus inclusion bodies.

Findings:

  • The infant's bowel obstruction was attributed to a Cytomegalovirus infection.
  • This case highlights a rare presentation of neonatal Cytomegalovirus affecting the gastrointestinal tract.

Implications:

  • Neonatologists and microbiologists should consider Cytomegalovirus as a potential cause of neonatal bowel obstruction.
  • Early diagnosis and management of neonatal GI CMV can prevent conditions mimicking necrotizing enterocolitis.

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