History, protohistory and prehistory of the Arabidopsis thaliana chromosome complement

We propose an evolutionary scenario that could have shaped the modern Arabidopsis thaliana genome, which began with the reduction in chromosome number from n=8 to n=5 in the past 4 million to 5 million years as a result of chromosome fusion. The scenario also includes three ancient polyploidizations: the most recent occurred in an early Brassicaceae with n=4 chromosomes 24 million to 40 million years ago. The two other polyploidizations occurred after the emergence of the Eudicots and the Angiosperms, respectively. Angiosperm evolution includes recurrent cycles of genome duplication and gene and chromosome reorganizations.