Related Experiment Video
Updated: Jul 29, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Life-threatening hypernatraemic dehydration in breastfed babies
R Shroff1, R Hignett, C Pierce
1Department of Nephrourology, Great Ormond Street Hospital for Children, London, UK.
Insights
Exclusively breastfed infants can develop severe hypernatraemic dehydration from insufficient milk intake. Health professionals need greater awareness to prevent this serious complication in newborns.
Area of Science:
- Pediatrics
- Neonatal Medicine
- Public Health
Background:
- Infant feeding practices significantly impact neonatal health outcomes.
- Hypernatraemic dehydration is a critical condition in newborns.
- Exclusive breastfeeding is recommended but requires adequate milk transfer.
Purpose of the Study:
- To report on severe cases of hypernatraemic dehydration in exclusively breastfed infants.
- To highlight the potential risks associated with inadequate breastfeeding.
- To emphasize the need for increased professional awareness and early detection.
Main Methods:
- Case series describing five infants with hypernatraemic dehydration.
- Clinical data collection on exclusively breastfed neonates.
- Review of feeding adequacy and hydration status.
Main Results:
- Five exclusively breastfed infants presented with life-threatening hypernatraemic dehydration.
- Inadequate breast milk intake was identified as the primary cause.
- Prompt medical intervention was required to manage the severe dehydration.
Conclusions:
- Inadequate breastfeeding can lead to severe hypernatraemia and dehydration in infants.
- Increased vigilance and education for healthcare providers are crucial for prevention.
- Early identification and management are vital to avoid severe infant morbidity and mortality.
Abstract:
We describe five babies, who were exclusively breast fed, with life-threatening complications of hypernatraemic dehydration secondary to inadequate breast feeding. An increased awareness among health professionals is required so that this potentially devastating condition can be prevented.
Related Concept Videos
Renal Tubule and Collecting Duct
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
Regulation of Water Intake
Disorder of Water Balance
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
Diabetes Insipidus I: Introduction
Diabetes Insipidus II: Pathophysiology
Hyperosmolar Hyperglycemic State

