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Methods to Test Endocrine Disruption in Drosophila melanogaster
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Methods to Test Endocrine Disruption in Drosophila melanogaster

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Epigenetics, evolution, endocrine disruption, health, and disease

David Crews1, John A McLachlan

  • 1Section of Integrative Biology, 2400 Speedway, University of Texas, Austin, Texas 78712, USA. crews@mail.utexas.edu

Endocrinology
|May 13, 2006
PubMed

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X-chromosome...
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Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
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Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
Endocrine Signaling01:45

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Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.