[Trial evaluation of familial asymptomatic bacteriuria]

Between September 1, 1987 and December 1, 1988, 57 cases of asymptomatic bacteriuria were distinguished in the group of 2,898 schoolgirls, aged between 15 and 20 years (mean 16.7 years). For screening purposes Griess'test modified by Sleigh was used. Bacteriologic tests have shown, that 12 out 57 mothers (21.05%) and 5 out of 39 sisters (12.82%) suffered from asymptomatic bacteriuria, while this pathology was diagnosed in 61 (2.10%) out of all control population, i.e. 66 girls. Incidence of the asymptomatic bacteriuria was 4.55% in the 66 mothers. The differences in the incidence of the infection between the whole population and mothers of the control group, and between sisters and mothers of girls with asymptomatic bacteriuria were statistically significant (p < .001 and p < .01, respectively). History of the urinary tract infections was significantly more frequent in girls with asymptomatic bacteriuria, their mothers and sisters than in the control group. Type of bacterial strains isolated from the urine, similar sanitary conditions in these families as well as the lack of ultrasonographically and renographically diagnosed urinary pathologies in 11 out of 13 girls whose mothers and sisters suffered from asymptomatic bacteriuria suggest that familial asymptomatic bacteriuria may have a genetic background.