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AgNOR measurements as indices of proliferation, ploidy and prognosis

J C Underwood1

  • 1Department of Pathology, University of Sheffield Medical School, Beech Hill Road, Sheffield S10 2RX.

Clinical Molecular Pathology
|October 1, 1995
PubMed
Abstract

No abstract available in PubMed .

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Nondisjunction01:21

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Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers.  Nondisjunction is common during anaphase I or anaphase II of meiosis.  Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold sister...

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