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Updated: Aug 8, 2026

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Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
Postmortem diagnosis of Factor V Leiden from paraffin wax embedded tissue
J S Webb1, G R Standen, C M Collins
1Molecular Haematology Unit, Department of Haematology, Bristol Royal Infirmary, Bristol BS2 8HW.
Clinical Molecular Pathology
|June 1, 1996
Abstract:
Activated protein C resistance resulting from Factor V Leiden is an important inherited thrombophilia disorder which is found in 3.5% of people in the UK. The genetic defect can be detected using the PCR and the diagnosis can be made postmortem from paraffin wax embedded tissue. The presence of Factor V Leiden should be sought in all cases of unexplained sudden death resulting from venous thromboembolism.

